Connect with us

Health

The future in your palm – a non-contact wearable that studies skin flux to estimate health

Published

on

The future in your palm – a non-contact wearable that studies skin flux to estimate health


This wearable tracks your health without touching you
| Video Credit:
The Hindu

William Blake could have scarcely estimated just the expanse that a palm full can contain, when he said ‘hold infinity in the palm of your hand’, but science today can give him a fair estimate. Smaller and smaller wearable devices, with the surface area the extent of a mere watch dial, have come to play, measuring all kinds of health parameters on the go – heart rate, blood oxygen, even continuous blood glucose levels. Here’s yet another wearable, but one with a difference. Researchers have zeroed in on a wearable that can study the streams of molecular substances that pass through the skin, as a measure of studying the health status of individuals. What is different is that this wearable is ‘non contact’ relying on an enclosed chamber immediately adjacent to the skin’s surface to do its job. 

A collaboration of American and South Korean experts from the domains of materials sciences, dermatology, engineering, bio-medics and chemistry worked to produce a small device, just about the size of a smartphone face, that has demonstrated unique capabilities to measure the flux of water vapour, volatile organic compounds  and carbon dioxide at various locations on the body, to examine not just skin health but general health too. The particular use has been to study wound healing properties in diabetes and has the additional advantage of non contact operation, therefore potential damage to fragile tissues can be avoided. 

Catch it early, cost-effectively

John A. Rogers who is the Lewis Simpson and Kimberly Querry Professor of Material Sciences and Engineering, Biomedical Engineering, and Neurological Surgery at the Northwestern University, U.S. and is steering the research says his team has been working on wearable technologies for about two decades now. “With the COVID pandemic, there began a heightened awareness of the value of technologies that could continuously monitor health status; catch very early signs of disease or infection or health complications, in remote and, cost-effective ways. We have introduced a number of skin interface devices for measuring vital signs like electrocardiograms, blood oxygenation, body temperature.” 

The wearable in question however is unique, he explains. “It is unique in the sense that the sensors don’t contact the skin. They’re actually separated from the skin, and instead of directly measuring underlying physiological processes- cardiac cycles, lung function, for example, we’re measuring, properties of the skin itself and measuring species that emerge from the body through the skin to the surrounding environment. And likewise, we are also measuring chemical species that can move from the environment into the body through the skin.”  

He adds this is something that people haven’t looked at before, and experiments have proved that there’s a lot of interesting information that emerges, related to wound healing but also basic health. The authors write up the results in a recent paper published in Nature journal. This technology can provide unique insights for clinical decision-makers managing conditions such as dermatological diseases and dermal wounds, but who are also interested in understanding the underlying pathophysiologies better. It can also monitor hazardous chemicals that enter the human body via the skin, making it a viable option to monitor the health of persons working in hazardous industries and zones. 

How the skin works

He continues to explain: The skin is a layered substance with a pretty good impermeable water barrier on the very surface – called the stratum corneum. Underneath that is the epidermis and then the dermis. Those tissues are fairly permeable to water. But the stratum corneum is a very thin layer of dead cells, and serves as a barrier. If that barrier did not exist, you’d have tons of water evaporating and water loss just coming out through all surfaces of the body. So, it performs a very critical function as a water barrier. If that’s compromised in any way, then, you can be at risk for dehydration and, degradation in the properties of the healthy living part of the skin, the epidermis and, and the dermis. 

Therefore, measuring water permeation through the skin can tell you a lot about the barrier function of the skin, and various skin disorders can reduce the barrier functions, Prof Rogers explains. “You can monitor that. Transcutaneous CO₂ for example, coming right through the surface of the skin is important, and physicians already know how to interpret that.” He adds that their assumption is that the device, with its capacity to read and measure the environmental species that enters the body through the skin will likely yield additional insights that physicians are not aware of yet. 

What the device does

The device itself, he describes, is like a small pocket, with wireless electronics that can transmit data to your phone. It also has a chamber that forms a microclimate when the device is sealed against the surface of the skin. Suspended within that chamber is a suite of sensors, very small semiconductor devices that can measure water, CO₂, and various volatile organic compounds. On the back, there is a valve that can be opened and closed through a wireless trigger. When the valve is closed and the device is on the surface of the skin, the sensors measure a gradual increase in the concentration of water vapor and CO₂. When the valve is open to the surrounding environment, the heightened concentrations of those species can dissipate because now those species can just diffuse out to the surrounding environment. We make measurements with the valve closed, then open, and so on. The rate at which those concentrations increase determines the flux.”  

These low-cost devices can just be adhered to the surface of the skin, and measure these properties continuously, without a physician having to be at call. The device can be mounted anywhere on body and track outward flux and also inward flux at the same time. 

An additional vital sign

Prof. Rogers says there has already been some interest in the device from the perfumery industry. And while it has not yet been studied in an environment where the patient has suffered burns, he added that it would be an exciting pathway to launch on. Once adequate data emerges from the device over a period of time, measurements off the skin might turn out to be an additional vital sign that doctors rely on to estimate the health of their patients, in addition to the conventional vital signs.



Source link

Continue Reading
Comments

Health

NEET-UG 2024: 26 MBBS students suspended for malpractice, 42 candidates debarred for three years

Published

on

NEET-UG 2024: 26 MBBS students suspended for malpractice, 42 candidates debarred for three years


In a major crackdown on irregularities in the NEET-UG 2024 examination, the Central Bureau of Investigation (CBI) and the National Testing Agency (NTA) have uncovered multiple instances of malpractice, including impersonation and the use of leaked question papers.
| Photo Credit: PTI

In a major crackdown on irregularities in the NEET-UG 2024 examination, the Central Bureau of Investigation (CBI) and the National Testing Agency (NTA) have uncovered multiple instances of malpractice, including impersonation and the use of leaked question papers.

Following the probe, the National Medical Commission (NMC) has directed medical colleges and institutions to immediately suspend 26 MBBS students found complicit in the violations. Additionally, admissions of 14 other students for the academic year 2024–25 have been cancelled, according to a senior official in the Union Health Ministry.

“The gravity of these offences threatens the credibility of the medical education system. The Commission has taken a serious view of the matter,” the official told The Hindu.

The latest directive comes just ahead of the NEET-UG 2025 examination, scheduled for May 4.

The NTA, which conducted NEET-UG 2024, had earlier flagged several cases as “Unfair Means (UFM)”, which were reviewed by its dedicated UFM Committee. Based on the committee’s findings, 42 candidates have been debarred from appearing in NEET-UG for three years—2024, 2025, and 2026—while nine others have been barred for two years, covering 2025 and 2026.

In addition, the candidature of 215 candidates remains under review as the investigation continues.

A senior Central Government official said the NMC maintains a zero-tolerance policy toward academic fraud. “Such misconduct compromises the sanctity of the examination process and directly threatens the standards of medical education and public trust,” the official said.

NEET-UG is India’s sole nationwide entrance examination for undergraduate medical programmes and is among the largest in terms of candidates. Allegations of malpractice have plagued the 2024 edition, with reports of question paper leaks leading to arrests in Bihar and raids in Gujarat. The case was subsequently handed over to the CBI.

Further controversy followed the declaration of results on June 4, 2024, when an unprecedented number of top scorers and statistically improbable marks triggered public outcry, legal challenges, and nationwide protests demanding a re-examination.



Source link

Continue Reading

Health

Rates of overweight exceed that of underweight in South Asia: Study on pre-pregnancy malnutrition

Published

on

Rates of overweight exceed that of underweight in South Asia: Study on pre-pregnancy malnutrition


According to the study ,there is a growing double burden of malnutrition among women in South Asia before pregnancy, as the prevalence of overweight now surpasses underweight, while anaemia and micronutrient deficiencies remain alarmingly high | Image used for representational purpose only
| Photo Credit: Getty Images

Highlighting a growing burden of malnutrition among married women in South Asia prior to conceiving, an analysis shows that prevalence of being overweight has surpassed that of being underweight.

Key findings

The analysis, published in The Lancet Regional Health Southeast Asia journal, also finds that short stature continues to be an issue, especially in India and Bangladesh, pointing to persistent concerns about malnutrition during early childhood and its long-term effects.

Researchers, including those from University College London, UK, and Population Council, India, analysed data collected through national surveys of South Asian countries — such as the National Family Health Survey in India — to understand the nutritional status of women before becoming pregnant.

The team published a series of papers related to aspects of pre-pregnancy nutrition, including prevalence of anaemia and micronutrient deficiency in population. They also reviewed public policies and programmes that deliver interventions on preconception nutrition.

“Our analysis of nationally-representative survey data reveals a growing double burden of malnutrition among preconception women in South Asia, as the prevalence of overweight (ranging from 29 per cent to 57.8 per cent) now surpasses that of underweight (4.6 per cent to 15.7 per cent) among married women,” the authors wrote.

Prevalence of short stature was estimated to be 10.7 per cent in India.

Lifestyle and diet associated health risks across South Asia

Urbanisation, migration, along with an increased availability of ultra-processed foods, even in rural areas, have driven a higher intake of fats, sugars, and calories, contributing to a worsening nutritional status, the authors said. They added that anaemia remains persistently high in South Asia, despite intervention efforts.

Anaemia prevalence in India has stagnated at 53.2 per cent during 2015-16 to 54 per cent during 2019-21, while it has marginally increased in Bangladesh (26 per cent in 2011-12 to 28.9 per cent in 2019-20), the study found. The team also looked at micronutrient deficiencies — another critical aspect of malnutrition among women in South Asia — by reviewing previously published studies.

For example, low serum ferritin — a marker of iron deficiency — is common in India (31 per cent to nearly 88 per cent) but much lower in Bangladesh, the researchers said. Deficiency of serum folate were found to be the highest in Sri Lanka (up to 52.5 per cent) and Pakistan (over 50 per cent), and lower in India (up to eight per cent) and Bangladesh (up to 30 per cent).

However, looking at red blood cell folate deficiency, the researchers found a high prevalence in India — ranging from 22 per cent to nearly 80 per cent — and Bangladesh (over 76 per cent). Vitamin D deficiency is a key concern, the authors said, with studies reporting over two thirds of women in South Asia being deficient.

Policy gaps and cultural barriers limit nutrition support

National survey data of Afghanistan shows that over 95 per cent of women in Afghanistan are low on vitamin D, the study said. Estimates of vitamin D deficiency appear to have reduced over time in India, but remain high in Pakistan and Afghanistan — both predominantly Muslim countries where most women wear clothing that reduces their skin’s exposure to the sun, the authors said.

Looking at public policies and programmes related to preconception nutrition in eight South Asian countries, the authors said that most countries, except Sri Lanka, lack a universal programme for health and nutrition screening and at providing essential micronutrients. The countries also lack a counselling on healthy eating and treatment for at-risk women, the authors said.

They added that in countries where supportive policies are present, implementation of comprehensive nutrition services for pre-pregnant women faces significant bottlenecks. Addressing these barriers is critical to improving intervention effectiveness, programme implementation, and informed decision-making, the team said.



Source link

Continue Reading

Health

WHO defends vaccine safety test standards

Published

on

WHO defends vaccine safety test standards


WHO emphasises the “gold standard” process for vaccine development already includes placebo testing for completely new vaccines, but requiring placebo testing for all vaccines, including existing ones adapted for new strains, could be unethical | Image used for representational purpose only
| Photo Credit: File Photo

The World Health Organization (WHO) on Thursday, May 1, 2025, said that “extremely high” safety standards are already applied in the development of vaccines, after reports about plans by the United States for a change to testing.

“We are confident in the assessments that go on around vaccines,” WHO vaccine chief Kate O’Brien told journalists in Geneva. “The safety of vaccines is held to an extremely high standard.” Ms. O’Brien was asked about a Washington Post report Thursday indicating that U.S. Health Secretary Robert F. Kennedy Jr. aims to shift the way vaccines are tested, requiring all new vaccines to undergo placebo testing.

The reported aim would be to increase safety and transparency but medical experts warn such a move could potentially limit access to vaccines and also undermine vaccine confidence. Ms. O’Brien stressed that the “gold standard” process for vaccine development already calls for placebo testing when developing completely new vaccines against diseases for which no immunisation options exist.

But she warned that existing vaccines that are altered to cover new strains for instance, could also be considered new vaccines. In such cases, it could be unethical to give test subjects a placebo — an inert product that does not prevent disease — instead of “vaccines that are life-saving that are already licensed”, she said.

“I think the important part of this is that the quality of clinical trials and safety assessments of those clinical trials are at the heart of what all vaccine development is about,” O’Brien said.

“It’s very important that we not constrain the ability and opportunity to develop better vaccines… The goal is to continue to develop improved vaccines.”

Combatting misinformation and upholding public trust

The WHO warned last week that outbreaks of vaccine-preventable diseases such as measles, meningitis, and yellow fever are on the rise globally amid misinformation and cuts to international aid.

Mr. Kennedy, a vaccine sceptic who has long promoted disproven theories linking childhood vaccines to autism, has also in recent days reportedly made false claims that the measles, mumps and rubella (MMR) vaccine contains “aborted fetus debris”.

“Some of these statements around what is used to produce measles and rubella vaccine, they’re not accurate statements,” Ms. O’Brien said. She urged people with power and influence to help boost confidence in the safety, efficacy and importance of vaccines, which have saved more than 150 million lives in the past five decades, according to the WHO.

“It really is the trust of communities, of people in communities, that forms the impact of vaccines,” she said.



Source link

Continue Reading

Trending

Copyright © 2025 Republic Diary. All rights reserved.