The conclave to elect a new pope has officially begun, with a Vatican official calling out “extra omnes” and the door to the Sistine Chapel shutting.

The Latin expression means “all out” and signals all those who aren’t eligible to vote for a new pope to leave the Sistine Chapel.

The order, delivered on Wednesday (May 7, 2025) by Archbishop Diego Ravelli allows the beginning of voting to elect the 267th pope to follow Pope Francis, history’s first Latin American pontiff.

With all the pomp, drama and solemnity that the Catholic Church can muster, 133 cardinals on Wednesday (May 7, 2025) began the secretive, centuries-old ritual, opening the most geographically diverse conclave in the faith’s 2,000-year history.

Two by two, the cardinals entered the Sistine Chapel chanting the meditative “Litany of the Saints” as Swiss Guards stood at attention. The hymn, and the one that followed, implores the saints and the Holy Spirit to help the cardinals find a new leader of the 1.4 billion-strong Catholic Church.

Cardinal Pietro Parolin, the secretary of state under Pope Francis and himself a leading contender to succeed as pope, assumed the leadership of the proceedings as the senior cardinal under age 80 and eligible to participate in the conclave.

Speaking in Latin, Cardinal Parolin stood before Michelangelo’s masterpiece “The Last Judgment”, and led the cardinals in a lengthy oath. Each one followed, placing his hand on the Gospel and promising to maintain utmost secrecy.

Hailing from 70 countries, the cardinals have been sequestered from the outside world, their cellphones surrendered and airwaves around the Vatican jammed to prevent all communications until they find a new leader.

Pope Francis named 108 of the 133 “princes of the church”, choosing many pastors in his image from far-flung countries such as Mongolia, Sweden and Tonga that had never had a cardinal before.

His decision to surpass the usual limit of 120 cardinal-electors and include younger ones from the “global south” — often marginalised countries with lower economic clout — has injected an unusual degree of uncertainty in a process that is always full of mystery and suspense, with smoke signals telling the world if a pope has been elected or not.

Many cardinals hadn’t met until last week and lamented they needed more time to get to know one another, raising questions about how long it might take for one man to secure the two-thirds majority, or 89 ballots, necessary to become the 267th pope.

“Wait and see, a little patience, wait and see,” said Cardinal Mario Zenari, the Vatican’s ambassador to Syria.

Earlier in the day, the dean of the College of Cardinals, Cardinal Giovanni Battista Re, presided over a morning Mass in St. Peter’s Basilica urging the voters to set aside all personal interests and find a pope who prizes unity. The world today needs a leader who can awaken consciences, he said.

“Let us pray that God will grant the church a pope who knows how best to awaken the consciences of all and the moral and spiritual energies in today’s society,” Cardinal Re said.

The awesomeness of the Sistine Chapel’s frescoes, and Michelangelo’s in particular, is meant to remind the cardinals of the weighty responsibility they bear. In his regulations for the conclave, St. John Paul II wrote that in the Sistine Chapel, “everything is conducive to an awareness of the presence of God”.

After the cardinals take their oaths, a senior cardinal delivers a meditation. The master of papal liturgical ceremonies, Archbishop Diego Ravelli, calls out “Extra omnes”, Latin for “all out”. Anyone not eligible to vote then leaves and the chapel doors close, allowing the work to begin.

The cardinals don’t have to take a first vote on Wednesday (May 7, 2025), but they are expected to. Assuming no winner is found, the Vatican said black smoke could be expected out of the Sistine Chapel chimney about 7 p.m.

The cardinals retire for the night and return on Thursday morning (May 8, 2025). They can hold up to two ballots in the morning and two in the afternoon until a winner is found.

While cardinals this week said they expected a short conclave, it will likely take at least a few rounds of voting. For much of the past century, it has taken between three and 14 ballots to find a pope. John Paul I — the pope who reigned for 33 days in 1978 — was elected on the fourth ballot. His successor, John Paul II, needed eight. Pope Francis was elected on the fifth in 2013.

While the cardinals are supposed to resist any “secular” influences in their choice, such lobbying abounded in Rome in the days before the conclave as various groups reminded cardinals of what ordinary Catholics want in a leader.

Young Catholics penned an open letter reminding cardinals that there is no church without young people, women and the laity. Conservative Catholic media slipped cardinals copies of a glossy book containing their assessments of contenders. Survivors of clergy sexual abuse warned cardinals that they would be held accountable if they failed to find a leader who will crack down on decades of abuse and cover-up.

Advocates for women’s ordination sent pink smoke signals over the Vatican to demand that women be allowed to be priests and participate in a conclave.

Even the White House got involved, posting a photo of President Donald Trump dressed as a pope. Trump said it was a joke, but the gesture was denounced by former Italian Premier Romano Prodi as “indecent” political interference in matters of faith that harked back to times when secular rulers habitually wielded religion to stay in power.

Lisette Herrera, a 54-year-old tourist from the Dominican Republic, was deeply moved to find herself by chance in Rome as the conclave began. She decided on Wednesday morning (May 7, 2025) to skip the Spanish Steps and Trevi Fountain and pray instead in St. Peter’s Square.

“I’m praying to the Holy Spirit for a young pope who would stay with us for a long time,” she said. “I don’t believe in conclave politics, I just feel that the Holy Spirit is here and that’s all we need to know.”

Armando Statti, a pilgrim from Crotone, Italy, said he expected cardinals would settle on a pope in the image of Francis or John Paul II.

“We hope he will be announced as soon as possible, for the sake of the whole world and for peace, and that he will embrace everyone,” he said.

Many challenges face the new pope and weigh on the cardinals — above all whether to continue and consolidate Francis’ progressive legacy on promoting women, LGBTQ+ acceptance, the environment and migrants, or roll it back to try to unify a church that became more polarised during his pontificate. The clergy sex abuse scandal hung over the pre-conclave talks.

Since Pope Francis chose 80% of the voters, continuity is likely, but the form it might take is uncertain and identifying front-runners has been a challenge.

But some names keep appearing on lists of “papabile”, or cardinals having the qualities to be pope.

— Cardinal Pietro Parolin, 70, an Italian who was Pope Francis’ secretary of state and the Vatican No. 2, is a leading contender.

Cardinal Luis Antonio Tagle attends a mourning Mass for Pope Francis on the fifth day of Novendiali (nine days of mourning after the Pope’s funeral) at St. Peter’s Basilica at the Vatican on April 30, 2025.
| Photo Credit:
Reuters

— Filipino Cardinal Luis Tagle, 67, is a top candidate to be history’s first Asian pope. He had a similarly high-profile job, heading the Vatican’s evangelisation office responsible for the Catholic Church in much of the developing world.

Cardinal Peter Erdo presides over Sunday Mass at the Basilica of Santa Francesca Romana in Rome on May 4, 2025.
| Photo Credit:
Reuters

— Hungarian Cardinal Peter Erdo, 72, the archbishop of Budapest, is a leading candidate representing the more conservative wing of the church.