Approximately three out of every five individuals in India succumb to death following a cancer diagnosis. Additionally, cancer-related mortalities have increased faster among females (1.2%-4.4% annual percentage change) than males (1.2%-2.4%) over the past decade, and are expected to continue rising over the coming two decades, found an analysis by the Indian Council of Medical Research (ICMR), based on figures presented by the Global Cancer Observatory (GLOBOCAN) 2022 estimates.
GLOBOCAN is an online database providing global cancer statistics and estimates of incidence and mortality in 185 countries for 36 types of cancer, and for all cancer sites combined.
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The analysis further notes that in India, childhood and reproductive age group individuals bear the lowest risk of developing (0.12%-2.4%) and dying (0.08%-1.3%) from cancer, compared with their middle-aged and geriatric counterparts, who have the highest risks of developing (8.3%-10.3%) and dying (5.5%-7.7%) from cancer.
“As the population of India transitions from the reproductive age group to the middle age and geriatric age group, India is anticipated to witness the highest cancer burden of all-time in near future, potentially exacerbated by the looming [cancer] epidemic,’’ notes the paper.
It adds that the five most prevalent cancers affecting both genders collectively account for 44% of the cancer burden in India.

The country is currently indicating that females exhibit higher ‘crude incidence’ and ‘crude mortality’ rates, compared with males, based on the population of 0.676 billion females and 0.731 billion males in 2022. The middle-aged and geriatric cohorts account for the heaviest (70%) cancer burden with higher crude rate incidents and deaths.
Crude rates are calculated by dividing the number of new cancers or cancer deaths observed during a given time period by the corresponding number of individuals in the population at risk.
GLOBOCAN 2022 estimates highlight cancer as a significant global health problem, and state that in the Southeast Asia region, India ranks third in terms of cancer incidence, and second for mortality, while globally, India ranks 121 in terms of crude rates.

For the analysis, a comprehensive-retrospective, cross-sectional study examining 36 types of cancer by gender, and across four distinct age groups (childhood, reproductive age, middle age, and geriatric age) in India, was conducted by the ICMR using the GLOBOCAN 2022 database.
“In the last two decades, life expectancy in India has increased by 5.6 years (9%) from 62.1 years in 2000 to 67.7 years in 2024. While communicable diseases were the leading contributors to mortalities in India, with socio-economic development and a concomitant increase in life expectancy, non-communicable diseases such as cardiovascular disease, stroke, diabetes-mellitus, and cancer have emerged as significant public health problems in India,’’ noted Khushwant Singh, the lead author of the paper.
These findings emphasise the importance of developing and implementing a resilient framework for targeted interventions aimed at managing gender-specific and prevalent common cancers through comprehensive strategies, Dr. Singh said.
Published – February 26, 2025 06:40 pm IST